Study reveals surprising evolutionary link between human fingers and fish anatomy
Nature’s Role in Evolution
For years, the evolution of hands and feet was believed to have originated from fish fins due to their similar appearance. However, recent research has revealed that the connection lies in genetic organization rather than physical structure. Denis Duboule, a professor, explained that instead of creating a new regulatory system for fingers, nature repurposed an existing one in the cloaca.
The Use of CRISPR in Evolutionary Studies
In a study comparing DNA regions in fish and mice, researchers used CRISPR technology to uncover the reuse of sequences that activated cloaca development in fish to regulate finger formation in terrestrial vertebrates. This discovery highlights the versatility of a genetic switch that transformed from an excretory to a locomotor function.
The Evolutionary Significance of Fingers
Fingers, which emerged around 380 million years ago, played a crucial role in enabling movement on land, object manipulation, and enhancing survival. The fact that their origin is traced back to a waste organ showcases how evolution maximizes available resources, ultimately leading to the diverse capabilities of modern humans.
